连续性肾脏替代治疗对严重脓毒血症的救治疗效

发布时间：2018-06-20 11:56

  本文选题：严重脓毒血症 + 连续性肾脏替代治疗　； 参考：《重庆医学》2016年08期

【摘要】：目的观察连续性肾脏替代治疗(CRRT)严重脓毒血症的疗效。方法选择严重脓毒血症患者22例,以行CRRT的患者作为治疗组(n=11),同期未行CRRT而行常规治疗的患者作为对照组(n=11)。两组均动态观察患者治疗前后乳酸、降钙素原、氧合指数、尿量等的变化,比较两组疗效及病死率。结果两组患者疾病严重程度(APACHEⅡ评分)及器官衰竭水平(SOFA评分)比较,差异无统计学意义(P0.05),治疗组短期内乳酸、降钙素原的下降,氧合指数的改善及尿量恢复均明显优于对照组,急性期(7d)病死率为9.1%,明显低于对照组(36.4%);但呼吸机使用时间、肾功能恢复情况及总体生存率等长期预后指标两组比较,差异无统计学意义(P0.05)。结论 CRRT可提高严重脓毒血症患者急性期抢救成功率,为原发病的治疗创造条件,但对长期预后影响不大。
[Abstract]:Objective to observe the effect of continuous renal replacement therapy (CRRT) on severe sepsis. Methods 22 patients with severe sepsis were treated with CRRT as the treatment group, and those who were not treated with CRRT but with routine treatment were used as the control group. The changes of lactic acid, procalcitonin, oxygenation index and urine volume were observed before and after treatment. Results there was no significant difference between the two groups in the severity of disease (Apache 鈪，

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