中医周期疗法治疗不孕症的用药规律及作用机制探析

发布时间：2018-05-28 19:54

本文选题：不孕症 + 中医周期疗法　；参考：《中国实验方剂学杂志》2017年20期

【摘要】：目的:应用数据挖掘方法分析和总结文献中中医周期疗法治疗不孕症的分期用药规律,探讨其作用机制的关键点。方法:检索1980—2016年有关中医周期疗法治疗不孕症的临床研究文献,建立Excel数据库,运用SPSS Clementine 12.0软件对数据进行处理分析。结果:共纳入文献85篇,涉及中药143味,应用频数共计3 609次。总结分期治疗的高频药物及组合规律,"补肾"贯穿治疗始终。结论:中医周期疗法治疗不孕症的分期治则治法为经后期益精养血,经间期活血化瘀、调畅血脉,经前期温肾助阳,月经期活血祛瘀生新。结合天癸相关理论,提出调肾中之天癸是中医周期疗法治疗不孕症的关键点。
[Abstract]:Objective: to analyze and summarize the law of using Chinese medicine by stages in the treatment of infertility by using data mining method, and to explore the key points of its action mechanism. Methods: to search the literature of clinical research on Chinese medicine periodic therapy for infertility from 1980 to 2016, establish Excel database, and use SPSS Clementine 12.0 software to process and analyze the data. Results: a total of 85 articles were included, involving 143 kinds of Chinese medicine, with a total of 3 609 times of application frequency. Sum up the high-frequency medicine and combination rule of stage therapy, "tonify kidney" throughout the treatment all the time. Conclusion: the periodic therapy of TCM for infertility is treated by stages: nourishing blood by supplementing essence and nourishing blood, activating blood circulation and removing blood stasis in interphase, regulating blood vessel, warming kidney and helping yang during premenstrual period, activating blood circulation and removing blood stasis in menstrual period. Based on the related theory of Tiangui, it is suggested that Tiangui in regulating kidney is the key point of TCM periodic therapy for infertility.
【作者单位】：山东中医药大学;山东中医药大学附属医院;
【基金】：国家自然科学基金面上项目(ZR2010HL063) 国家中医药管理局张志远全国名老中医药专家传承工作室项目(国中医药人教发【2013】47号)
【分类号】：R271.14;TP311.13

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