中医分期论治对咳嗽变异性哮喘患儿肺功能的影响

发布时间：2018-04-24 05:10

本文选题：咳嗽变异性哮喘 + 中医药　；参考：《湖南中医药大学》2013年硕士论文

【摘要】：目的：观察中医分期治疗咳嗽变异性哮喘(Cough variant asthma,CVA)患儿肺功能的变化,探讨中药治疗CVA的作用机理。方法：将60例CVA患儿随机分为治疗组和对照组,每组30例。治疗组采用中医分期(发作期口服温肺化痰饮,缓解期口服补肺健脾饮)治疗；对照组(孟鲁司特钠嚼服,发作期加服用氨茶碱),两组总疗程均为3个月。两组分别在治疗前、后行肺功能检查。结果：1.疾病疗效：治疗组总有效率96.67%,对照组总有效率93.33%,结果示两组差异无统计学意义(P0.05),两组疾病疗效相当。2.中医证候疗效：治疗组总有效率96.67%,对照组总有效率86.67%,结果示两组差异有显著统计学意义(P0.01),治疗组明显优于对照组。3.肺功能各项指标治疗组和对照组治疗后比较两组间差异无统计学意义(P0.05),其中反映大气道功能的的指标(FVC、 FEV1、 FEV1/FVC、PEF)两组治疗前后比较差异无统计学意义(P0.05),反映小气道功能的指标(FEF25、 FEF50、FEF75)两组治疗前后比较差异有显著性差异(P0.01) 结论：中医分期论治CVA与西药组比较其疾病疗效相当；但中医症候疗效明显优于西药组；CVA主要表现为小气道功能障碍,两组均具有改善小气道功能障碍的作用。
[Abstract]:Objective: to observe the changes of lung function in children with cough variant asthma (CVA) treated by stages with traditional Chinese medicine (TCM), and to explore the mechanism of TCM in the treatment of CVA. Methods: 60 children with CVA were randomly divided into treatment group (n = 30) and control group (n = 30). The treatment group was treated by traditional Chinese medicine stages (Wenfei Huatan decoction in attack period and Bufei Jianpi decoction in remission period), while in control group (montelukast sodium chewing, aminophylline plus aminophylline in attack period, the total course of treatment was 3 months). Lung function tests were performed before and after treatment in both groups. The result is 1: 1. The total effective rate of the treatment group was 96.67 and that of the control group was 93.33.The results showed that there was no significant difference between the two groups (P 0.05). The curative effect of the two groups was equal to that of the control group (P 0.05). The curative effect of TCM syndrome: the total effective rate of the treatment group was 96.67 and the total effective rate of the control group was 86.67.The results showed that the difference between the two groups was statistically significant (P 0.01), and the treatment group was obviously superior to the control group. 3. There was no significant difference in pulmonary function between the two groups after treatment. There was no significant difference between the two groups before and after treatment, and there was no significant difference between the two groups before and after treatment (P 0.05), which reflected the function of the small airway, including FVC, FEV1, FEV1 / FVCnPEF. FEF25, FEF50 and FEF75) there was significant difference between the two groups before and after treatment (P 0.01). Conclusion: compared with the western medicine group, the curative effect of CVA treated by stages in TCM is similar to that in the western medicine group, but the curative effect of TCM syndrome is obviously superior to that of the western medicine group. The main manifestation of TCM is small airway dysfunction, and both groups have the effect of improving the small airway dysfunction.
【学位授予单位】：湖南中医药大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R272

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