舒芬太尼复合丙泊酚靶控输注对肺癌根除术患者的麻醉效果观察

发布时间：2018-11-22 16:26

【摘要】：目的:对肺癌根除术患者使用舒芬太尼复合丙泊酚靶控输注进行麻醉,观察效果。方法:选取90例2013年1月~2015年3月至我院进行诊治并择期行肺癌根治术的患者,随机分为对照组和观察组,每组45例。所有患者采取相同的麻醉诱导方法,对照组给予0.4μg/kg舒芬太尼以及1.0mg/kg维库溴铵静脉注射,术中采用3.5μg/m L丙泊酚靶控输注以及每小时0.2μg/kg舒芬太尼静脉恒速注射;观察组给予3μg/m L舒芬太尼靶控输注以及0.8mg/kg维库溴铵静脉注射,术中采用3.5μg/m L丙泊酚和3μg/m L舒芬太尼靶控输注。统计和比较两组麻醉诱导期血压和心率变化情况以及术后呼吸恢复时间、拔管时间以及睁眼时间。结果:1麻醉诱导前两组血压和心率进行比较,差异不显著(P0.05);麻醉诱导后两组收缩压、舒张压以及心率均明显降低,与诱导前相比,差异显著(P0.05),但两组之间比较无显著差异(P0.05);2手术后,两组呼吸恢复时间进行比较,差异不显著(P0.05),但观察组拔管时间和睁眼时间均明显少于对照组,两组之间进行统计学比较,差异显著(P0.05)。结论:应用舒芬太尼复合丙泊酚靶控输注对肺癌根治术患者进行麻醉,不会明显改变患者麻醉诱导期的血流动力学特征,但是对于术后的恢复具有显著的改善效果,明显缩短了拔管时间和睁眼时间。
[Abstract]:Objective: to observe the effect of target-controlled infusion of sufentanil and propofol in patients with lung cancer eradication. Methods: from January 2013 to March 2015, 90 patients with lung cancer underwent radical resection and were randomly divided into control group (n = 45) and observation group (n = 45). All patients received the same anesthetic induction. The control group received 0.4 渭 g/kg sufentanil and 1.0mg/kg vecuronium intravenously. 3. 5 渭 g / mL propofol target controlled infusion and 0. 2 渭 g/kg sufentanil intravenously injection were used. The observation group was given 3 渭 g / mL sufentanil target-controlled infusion and 0.8mg/kg vecuronium intravenously. During the operation, 3.5 渭 g / mL propofol and 3 渭 g / mL sufentanil were used for target-controlled infusion. The changes of blood pressure and heart rate, postoperative respiratory recovery time, extubation time and eye opening time were statistically analyzed and compared between the two groups. Results: 1 there was no significant difference in blood pressure and heart rate between the two groups before anesthesia induction (P0.05); After anesthesia induction, systolic blood pressure, diastolic blood pressure and heart rate of the two groups were significantly lower than those before induction (P0.05), but there was no significant difference between the two groups (P0.05). 2After operation, there was no significant difference in respiratory recovery time between the two groups (P0.05), but the time of extubation and eye opening in the observation group was significantly less than that in the control group, and the difference between the two groups was significant (P0.05). Conclusion: sufentanil combined with propofol target-controlled infusion for patients undergoing radical resection of lung cancer does not significantly change the hemodynamic characteristics of the patients during anesthesia induction, but has a significant effect on postoperative recovery. The time of extubation and eye opening were shortened obviously.
【作者单位】：长乐市医院麻醉科;
【分类号】：R614;R734.2

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