Amelioration of mitochondrial dysfunction in heart failure t

发布时间：2021-01-14 08:50

　　OBJECTIVE To determine the functional role of hydrogen sulfide（H₂S） in protecting against mitochondrial dysfunction in heart failure through the inhibition of Ca²⁺/calmodulin-dependent protein kinaseⅡ（Ca MKⅡ） using wild type and CSE knockout mouse models.METHODS Continuous subcutaneous injection isoprenaline(7.5 mg·kg^-1 per day),once a day for 4 weeks to induce heart failure in male C57BL/6（6-8 weeks old） mice and CSE-/-mice.150 μmol·L^-1 H₂O... 

【文章来源】：中国药理学与毒理学杂志. 2017,31(10)北大核心

【文章页数】：1 页


本文编号：2976603