高温高湿环境肢体火器伤细菌学改变的研究

发布时间：2018-05-13 23:14

本文选题：高温高湿环境 + 肢体　；参考：《解放军预防医学杂志》2002年02期

【摘要】：目的 :为高温高湿环境下火器伤后软组织清创的时机、方法及抗生素的应用提供依据。方法 :将犬随机分为高温高湿 (HHE)组和常温常湿 (OE)组 ,于火器伤后 0、4、6、8、12、2 4h进行大体情况、细菌学定量和定性变化等指标的检测。结果 :伤肢肿胀、组织坏死和动物死亡时间 ,HHE组均较OE组提前及严重。细菌学定量检测HHE组火器伤伤道细菌数在同一时间点比OE组高 ,OE组 12h细菌数目达到可引起感染的临界数值 ,而HHE组 8h时细菌数即达临界数值。细菌定性检测 ,两组弹道局部均为表面菌群 ;血液中OE组只有表面菌群 ,HHE组除表面菌群外还有肠道菌群。结论 :高温高湿环境下火器伤后细菌繁殖快 ,感染时间提前且严重 ,肠道细菌容易入血 ,因此处理更应强调尽早、彻底的清创和早期使用广谱抗生素
[Abstract]:Objective: to provide evidence for debridement of soft tissue after firearm injury in high temperature and high humidity environment. Methods: dogs were randomly divided into high temperature and high humidity HHEG group and normal temperature and normal humidity group. The gross condition, bacteriological quantitative and qualitative changes were detected at 0 ~ (4) h ~ (th) ~ (12) h after firearm injury. Results: the swelling of injured limbs, tissue necrosis and the time of animal death were earlier and more serious in HHE group than in OE group. Bacteriological quantitative analysis showed that the number of bacteria in firearm wound in HHE group was higher than that in OE group at the same time point, and that in OE group was higher than that in OE group at 12h, but that in HHE group reached critical value at 8h. Qualitative examination of bacteria showed that the surface microflora was found in both groups, and that in the OE group, there were intestinal flora besides the surface flora in the OE group. Conclusion: under the condition of high temperature and high humidity, the bacteria propagate quickly, the infection time is early and serious, and the intestinal bacteria enter blood easily. Therefore, the treatment should emphasize early, thorough debridement and early use of broad-spectrum antibiotics.
【作者单位】：第一军医大学南方医院创伤骨科第一军医大学南方医院创伤骨科第一军医大学南方医院创伤骨科第一军医大学南方医院检验科第一军医大学南方医院检验科第一军医大学高温教研室
【基金】：“军队”九五医药卫生杰出中青年基金资助项目 (No.98G0 0 4)
【分类号】：R826

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