清热消痛汤联合康妇消炎栓治疗湿热瘀结型盆腔炎性疾病后遗症的临床研究

发布时间：2018-05-15 20:03

本文选题：盆腔炎性疾病后遗症 + 清热消痛汤　；参考：《福建中医药大学》2017年硕士论文

【摘要】：目的:观察清热消痛汤联合康妇消炎栓治疗湿热瘀结型盆腔炎性疾病后遗症的临床疗效,客观地评价本方在改善患者临床症状、体征方面的有效性,提高治愈率及减少复发率的可能性。方法:采用随机分组的方法将60例辨证为湿热瘀结型盆腔炎性疾病后遗症的患者随机分为A组(治疗组:清热消痛汤联合康妇消炎栓组)、B组(对照组:妇科千金片联合康妇消炎栓组),每组各30例。通过观察患者用药前和用药后1个疗程、2个疗程、3个疗程以及停药后1个月的临床变化,并进行统计学分析,对其临床疗效进行评价。结果:1.综合疗效比较:治疗1个疗程后,治疗组的总有效率80%,对照组的总有效率73.33%,两组组间比较无显著差异(P0.05),说明两组均能改善患者临床症状,且疗效相当;治疗2个疗程后,治疗组的总有效率90.00%对照组的总有效率76.67%,两组组间比较有差异(P0.05),说明治疗组综合疗效优于对照组;治疗3个疗程后,治疗组的总有效率93.33%,对照组的总有效率80.00%,两组组间比较有差异(P0.05),说明治疗组的综合疗效仍优于对照组;停药1个月后,治疗组的总有效率90.00%,对照组的总有效率73.33%,有统计学意义,说明治疗组的综合疗效仍高于对照组。2.中医证候比较:治疗3个疗程后,治疗组的中医证候总有效率96.67%,对照组的中医证候总有效率83.33%,两组组间比较差异有统计学意义(P0.05),说明治疗组的中医证候疗效的改善优于对照组。3.局部体征比较:治疗3个疗程后两组患者局部体征积分对比,差异有统计学意义(P0.05),说明治疗组的体征改善优于对照组。4.超声比较:治疗3个疗程后比较盆腔超声检查结果(盆腔积液和附件区包块),无统计学差异(P0.05),说明2组均能减少盆腔积液和缩小附件区包块,且疗效相当。5.可行性分析:两组治疗前在年龄、病程、病情、中医证候、局部体征等方面差异无统计学意义(P0.05)。6.治疗组的疗效结果与不同年龄、不同病程及不同的病情程度患者相关性无明显统计学差异(P0.05)。7.安全性检测:两组患者治疗前后分别测定血常规、尿常规、粪常规、肝功能、肾功能、常规心电图均无明显异常,这表明清热消痛汤联合康妇消炎栓用药安全可靠,尚无毒副作用。结论:清热消痛汤联合康妇消炎栓能改善湿热瘀结型盆腔炎性疾病后遗症患者的临床症状及体征,减少盆腔积液和缩小附件区包块,于停药1个月后,仍能维持较好的治疗效果,减少其复发率,并且使用安全。
[Abstract]:Objective: to observe the clinical effect of Qingre Xiaotong decoction combined with Kangfuxiaoyan suppository in treating the sequelae of damp-heat stasis type pelvic inflammatory disease, and to evaluate objectively the effectiveness of the prescription in improving the clinical symptoms and signs of the patients. Improve the cure rate and reduce the possibility of recurrence. Methods: 60 patients were randomly divided into two groups: group A (treatment group: Qingre Xiaotong decoction combined with Kangfu Xiaoyan suppository group) (control group: gynecological Qianjin group: control group: gynecological Qianjin group). Combined with Kangfu Xiaoyan suppository group, 30 cases in each group. The clinical changes of patients before and after one course of treatment, 2 courses of treatment, 3 courses of treatment and 1 month after withdrawal were observed, and the clinical efficacy was evaluated by statistical analysis. The result is 1: 1. Comprehensive curative effect comparison: after one course of treatment, the total effective rate of the treatment group was 80%, the total effective rate of the control group was 73.33, and there was no significant difference between the two groups (P 0.05), which indicated that both groups could improve the clinical symptoms of the patients, and the curative effect was the same; after two courses of treatment, The total effective rate of the treatment group was 90.00%, the total effective rate of the control group was 76.67. The difference between the two groups was P 0.05, which indicated that the comprehensive curative effect of the treatment group was better than that of the control group. The total effective rate of the treatment group was 93.33 and the total effective rate of the control group was 80.00.The difference between the two groups shows that the comprehensive curative effect of the treatment group is still superior to that of the control group. It shows that the comprehensive curative effect of the treatment group is still higher than that of the control group. Comparison of TCM syndromes: after three courses of treatment, the total effective rate of TCM syndromes in the treatment group was 96.6767 and that in the control group was 83.33.The difference between the two groups was statistically significant, indicating that the improvement of the curative effect of TCM syndrome in the treatment group was better than that in the control group. Comparison of local physical signs: after 3 courses of treatment, the scores of local signs of the two groups were compared, the difference was statistically significant (P 0.05), indicating that the improvement of physical signs in the treatment group was better than that in the control group. 4. Ultrasound comparison: after three courses of treatment, the results of pelvic ultrasound examination were compared (pelvic effusion and adnexal mass were not significantly different (P 0.05), indicating that both groups could reduce pelvic effusion and reduce adnexal mass, and the curative effect was equal to. 5. Feasibility analysis: there was no significant difference between the two groups in age, course of disease, condition, TCM syndromes, local signs and so on before treatment. In the treatment group, there was no significant difference in the correlation between the curative effect and the patients of different ages, different course of disease and different degree of disease. Safety test: blood routine, urine routine, fecal routine, liver function, kidney function, routine electrocardiogram were not significantly abnormal before and after treatment, which indicated that Qingre Xiaotong decoction combined with Kangfu Xiaoyan suppository was safe and reliable. There are no side effects. Conclusion: Qingre Xiaotong decoction combined with Kangfu Xiaoyan suppository can improve the clinical symptoms and signs of the sequelae of damp-heat stasis type pelvic inflammatory disease, reduce pelvic effusion and reduce the adnexal block. Can still maintain good therapeutic effect, reduce its recurrence rate, and use safely.
【学位授予单位】：福建中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R271.9

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