人体死后不同时间玻璃体液化学成分的变化趋势

发布时间：2018-05-21 13:07

本文选题：法医学 + 人玻璃体液　；参考：《四川大学学报(医学版)》2006年06期

【摘要】：目的测定人死后玻璃体液化学成分含量,对多种化学指标进行分析,建立各自的回归方程,使玻璃体液检测能更广泛地应用于法医实践。方法用日本产OLYMPUSAU400自动生化仪对死后时间在0.5~216h的126例尸体玻璃体液中葡萄糖等11种成分的含量进行测定。结果1玻璃体液中葡萄糖、钠、氯随死后时间的延长而逐渐下降;尿素、肌酐、尿酸、钾、钙、镁、无机磷、微量蛋白随死后时间的延长而逐渐升高。葡萄糖、钾离子和无机磷与死亡时间的相关性好(r=-0.824,0.967,0.880),而尿酸和微量蛋白则不能用于推断死亡时间(r=0.350,0.153)。2死后72h内,死亡时间的逐步回归方程为Y=-35.15+6.05X,R2=0.957,X代表玻璃体液钾离子浓度。Y=-27.83+5.49X1-1.35X2,R2=0.960,X1、X2分别代表玻璃体液钾离子、葡萄糖浓度。Y=-16.37+3.93X1-2.29X2+5.36X3,R2=0.966,X1、X2、X3分别代表玻璃体液钾离子、葡萄糖、无机磷浓度。结论1玻璃体液中葡萄糖等11种化学成分的含量随死后时间的延长而改变,其中钾离子在死后72h内与死亡时间最具有线性关系。2用逐步回归法建立多元回归方程推断死亡时间,可以提高对死亡时间估计的准确性。
[Abstract]:Objective to determine the content of chemical components of vitreous body fluid after death, analyze various chemical indexes and establish their regression equations, so that the detection of vitreous body fluid can be more widely used in forensic practice. Methods the contents of glucose and other 11 components in vitreous body fluid of 126 cadaveric patients with postmortem time of 0.5 ~ 216h were determined by OLYMPUSAU400 automatic biochemical instrument made in Japan. Results 1 glucose, sodium and chlorine in vitreous body fluid decreased gradually with the prolongation of postmortem time, and urea, creatinine, uric acid, potassium, calcium, magnesium, inorganic phosphorus and trace protein increased gradually with the prolongation of postmortem time. The correlation between glucose, potassium ion and inorganic phosphorus and the time of death was good. However, uric acid and trace protein could not be used to estimate the time of death within 72 hours after death. The stepwise regression equation of the time of death is that the concentration of potassium ion in vitreous body fluid. Y-27.83 5.49X1-1.35X2ON0.960X1X _ 2 represents potassium ion in vitreous body fluid, and the concentration of glucose. Y-16.37 3.93X1-2.29X2 5.36X3R2O0.966X _ 1X _ 2X _ 3 represents potassium ion of vitreous body fluid, and the concentration of glucose and inorganic phosphorus represents vitreous body fluid potassium ion, respectively. Conclusion (1) the contents of 11 chemical components such as glucose in vitreous body fluid changed with the prolongation of postmortem time, and potassium ion had the most linear relationship with the time of death within 72 h after death. 2 the multiple regression equation was established to estimate the time of death by stepwise regression method. It can improve the accuracy of time of death estimation.
【作者单位】：四川大学华西基础医学与法医学院法医病理学教研室四川大学华西医院实验医学科四川大学华西医院实验医学科四川大学华西基础医学与法医学院法医病理学教研室四川大学华西基础医学与法医学院法医病理学教研室
【分类号】：D919

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