热毒清方治疗热毒蕴结型肛痈的临床研究

发布时间：2018-05-15 22:05

本文选题：肛痈 + 保留灌肠　；参考：《河南中医药大学》2016年硕士论文

【摘要】：目的：回顾采用热毒清方治疗肛痈(热毒蕴结型),观察总结其对肛痈(热毒蕴结型)的临床疗效,及有无不良反应。并通过对治疗药物的现代药理研究及治疗方法的探讨,初步探讨其治疗机制,为临床上.的运用提供科学的依据。方法：选择201 4年07月～2016年01月来自于郑州市大肠肛门病医院,符合肛痈(热毒蕴结型)门诊患者60例。由就诊先后顺序随机的分为对照组30例(盐酸左氧氟沙星注射液与奥硝唑氯化钠注射液)抗生素静脉滴注,治疗组30例抗生素静脉滴注(盐酸左氧氟沙星注射液联合奥硝唑氯化钠注射液)联合热毒清方保留灌肠。7天为一疗程,观察两组在治疗前和治疗7天后,患者肛门疼痛、肿块范围大小、全身情况、肿块质地、临床总疗效、不良反应情况。记录治疗过程中相关症状和体征的变化,并分析比较两组患者在肛门部疼痛情况,肛门肿块范围大小的变化以及全身情况、肿块质地和临床总疗效及不良反应等方面的差异,最后数据的分析是采用统计学软件SPSS19.0处理。结果：经统计学分析,两组患者在基本情况上具有可比性(P0.05)1.比较治疗后两组肛门疼痛情况,所得治疗组优于对照组,有显著差异,(P0.05)具有统计学意义,表明热毒清方能明显减轻患者肛门部的疼痛。2.治疗后两组肿块范围大小变化情况对比,所得治疗组优于对照组,有显著差异(P0.05),有统计学意义,表明热毒清方能促进患者肛门部肿块的消散吸收,范围大者,可以缩小其范围。3.治疗后两组全身情况方面比较,所得治疗组优于对照组,有显著差异(P0.05),具有统计学意义,表明热毒清方在改善患者全身情况方面疗效显著。4.治疗后两组肿块质地情况比较,所得治疗组优于对照组,有显著差异(P0.05),具有统计学意义,表明热毒清方可使肿块软化直至最后被消散。5.比较两组治疗后治愈情况,治疗组治愈8例,对照组治愈2例,经统计学分析有差异(P0.05),说明治疗组治疗效果明显优于对照组。6.两组患者在治疗前后均未出现任何不良反应情况。结论：抗生素联合热毒清方治疗肛痈(热毒蕴结型)疗效肯定,能有效缓解患者肛门部疼痛,促进患者肛门部脓肿肿块消散吸收,范围大者则能缩小肿块范围,降低了炎症刺激,并且没有发现不良反应,安全可行,是治疗肛痈(热毒蕴结型)的有效方法。本研究治疗肛痈(热毒蕴结型),采用抗生素联合中药保留灌肠,是中西医结合的充分体现,不仅安全有效、价格便宜而且治疗操作方便、无创伤,免除了手术带来的痛苦,患者也比较接受。
[Abstract]:Objective: to review the clinical effect of Reduqing recipe in the treatment of anal carbuncle (heat toxin accumulation type), and to observe its clinical effect on anal carbuncle (heat toxin accumulation type) and whether it has adverse reactions. And through the modern pharmacological research and the treatment method of the treatment drugs, the treatment mechanism is preliminarily discussed, which is clinical. To provide scientific basis for the use of. Methods: a total of 60 outpatients with anal carbuncle (heat and toxin accumulation type) from July 2014 to January 2016 were selected from Zhengzhou large bowel and anal disease hospital. The patients were randomly divided into control group (levofloxacin hydrochloride injection and ornidazole sodium chloride injection). 30 patients in the treatment group were treated with antibiotic intravenous drip (levofloxacin hydrochloride injection combined with ornidazole sodium chloride injection) and retention enema for 7 days as a course of treatment. Anus pain was observed before treatment and 7 days after treatment. Mass size, systemic condition, mass texture, total clinical efficacy, adverse reactions. To record the changes of symptoms and signs in the course of treatment, and to analyze and compare the differences between the two groups in the anus pain, the size of the anal mass, the whole body, the texture of the mass, the clinical curative effect and the adverse reactions. The final data analysis is the use of statistical software SPSS19.0 processing. Results: by statistical analysis, the two groups of patients in the basic conditions can be comparable P 0.05 1. Compared with the two groups after the treatment of anal pain, the treatment group is superior to the control group, there is a significant difference (P0.05), indicating that RDQ can significantly reduce the pain of anal pain. 2. After treatment, the changes of the tumor range in the two groups were compared. The results showed that the treatment group was superior to the control group, and there was significant difference (P 0.05), which indicated that Reduqing prescription could promote the dissipation and absorption of the anal mass of the patients, and the range of the treatment group could be reduced by 3. 3. After treatment, compared with the control group, the treatment group is better than the control group, there is a significant difference (P 0.05), there is statistical significance, indicating that the effect of Reduqing prescription in improving the patients' whole body condition is significant. 4. After treatment, the texture of the tumor in the treatment group was better than that in the control group, and there was a significant difference between the treatment group and the control group (P 0.05), which indicated that RDQ could soften the mass until it was finally dissipated. There were 8 cases cured in the treatment group and 2 cases in the control group, which showed that the therapeutic effect of the treatment group was better than that of the control group. There were no adverse reactions in both groups before and after treatment. Conclusion: the treatment of anal carbuncle with antibiotics combined with Reduqing prescription is effective in relieving anal pain, promoting the dissipation and absorption of anal abscess, and reducing the area of the mass in large range. It is safe and feasible to treat anal carbuncle. In this study, the treatment of anal carbuncle (heat toxin accumulation knot type, antibiotics combined with traditional Chinese medicine retention enema) is a full embodiment of integrated Chinese and western medicine, which is not only safe and effective, cheap and easy to treat, but also has no trauma, and avoids the pain caused by the operation. Patients are also more receptive.
【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R266

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