特质愤怒影响攻击行为的脑结构及功能基础

发布时间：2018-06-13 20:11

本文选题：特质愤怒 + 攻击行为　；参考：《西南大学》2017年硕士论文

【摘要】：攻击行为的发生会对目标对象造成伤害,甚至威胁到对方的生命,给周围的人们带来恐慌,影响社会的安定有序和国家的和谐发展,因而受到社会学、心理学的广泛关注。在多年研究的基础上,研究者提出了许多关于攻击行为的理论模型,这些理论模型从不同的方面探讨了攻击行为产生的内在机制。其中,最具代表性的是一般攻击模型(GAM),该模型认为,特质愤怒作为一种持久而稳定的人格特质会影响个体的攻击行为,并且个体的内在状态在其中发挥着重要的作用。然而,迄今为止,鲜有研究探讨特质愤怒影响攻击行为的神经机制。基于此,本研究从一般攻击模型(GAM)的视角出发,以大学生作为调查对象,选取高低特质愤怒个体作为被试,采用修改版的Taylor攻击范式以及脑成像技术考察特质愤怒影响攻击行为的脑结构及功能基础。研究一采用基于体素的形态测量学(VBM)技术探讨特质愤怒的脑结构基础,并进一步分析特质愤怒影响攻击行为的脑形态学机制。结果表明,高特质愤怒个体左侧中央后回、左侧顶上回和左侧距状回的灰质体积显著大于低特质愤怒个体,进一步分析发现,左侧中央后回的灰质体积与反应性攻击行为呈显著正相关,左侧距状回的灰质体积与行为激发效应呈显著负相关。也就是说,左侧中央后回可能是特质愤怒影响反应性攻击行为的脑结构基础,而左侧距状回可能是特质愤怒影响行为激发效应的脑结构基础。研究二采用静息态功能磁共振成像技术及其局部一致性和功能连接的方法探讨特质愤怒的脑功能基础,并进一步分析特质愤怒影响攻击行为的脑功能机制。局部一致性分析结果表明,高低特质愤怒个体的右侧后扣带回、右侧中央前回、左侧顶下回、右侧颞下回、左侧枕中回以及左侧楔前叶的Re Ho值差异显著,进一步分析发现,右侧中央前回、右侧颞下回、左侧枕中回的Re Ho值与反应性攻击行为相关显著,而右侧后扣带回的Re Ho值与行为激发效应相关显著。也就是说,右侧中央前回、右侧颞下回以及左侧枕中回可能是特质愤怒影响反应性攻击行为的脑功能基础,而右侧后扣带回可能是特质愤怒影响行为激发效应的脑功能基础。功能连接分析结果表明,高低特质愤怒个体的右侧杏仁核与双侧内侧OFC以及左侧颞极与双侧内侧OFC的功能连接强度差异显著,右侧杏仁核与右侧ACC的功能连接强度边缘显著,进一步分析发现,左侧颞极与双侧内侧OFC的功能连接强度与反应性攻击行为相关显著。也就是说,左侧颞极与双侧内侧OFC的功能连接可能也是特质愤怒影响反应性攻击行为的脑功能基础。综上所述,本研究从一般攻击模型(GAM)的视角出发,探讨了特质愤怒影响攻击行为的神经机制,该神经机制不仅涉及自动化的认知加工脑区,还涉及努力控制脑区,为攻击行为的一般攻击模型(GAM)以及努力控制理论提供了脑科学证据,对理解特质愤怒与攻击行为的关系具有积极的推动作用。
[Abstract]:The occurrence of attack will cause harm to the target object, even threaten the person's life, bring panic to the people around, influence the stability and order of the society and the harmonious development of the country, so it is widely concerned with the sociology and psychology. On the basis of years of research, the researchers have put forward a lot of theoretical models about the behavior of attack. These theoretical models discuss the inherent mechanism of attack from different aspects. Among them, the most representative is the general attack model (GAM). The model believes that the trait anger, as a persistent and stable personality trait, affects the individual's attack behavior, and the internal state of the body plays an important role in it. So far, few studies have been made to explore the neural mechanism of idiosyncratic anger affecting attack behavior. Based on this, this study, starting from the perspective of the general attack model (GAM), takes college students as the subject of investigation, chooses high and low idiosyncratic angry individuals as subjects, uses the modified Taylor attack paradigm and brain imaging technology to investigate the impact of idiosyncratic anger. The brain structure and functional basis of attack behavior. A study of the brain structural basis of idiosyncratic anger using voxel based morphometry (VBM) and further analysis of the brain morphological mechanism of idiosyncratic anger affecting aggressive behavior. The product was significantly larger than the low trait anger individual. Further analysis showed that the volume of gray matter in the left posterior central gyrus was significantly positively correlated with reactive aggression, and the volume of gray matter in the left lateral gyrus was negatively correlated with the behavioral stimulation effect. Base, and left lateral gyrus may be the brain structural basis for the effect of idiosyncratic anger on behavioral stimulation. Study two the resting state functional magnetic resonance imaging (fMRI) and its local conformance and functional connection were used to explore the brain functional basis of idiosyncratic anger and to further analyze the brain function mechanism of idiosyncratic anger affecting attack behavior. The results showed that the Re Ho values of the right posterior cingulate gyrus, right anterior central gyrus, left parietal gyrus, right inferior temporal gyrus, left occipital gyrus and left anterior wedge lobe were significantly different. Further analysis showed that the right anterior central gyrus, right temporal gyrus, and the Re Ho value of the left occipital gyrus were significantly related to reactive attack behavior. The Re Ho value of the right posterior cingulate gyrus has a significant correlation with the behavioral stimulation effect. That is to say, the right anterior central gyrus, right inferior temporal gyrus, and left occipital gyrus may be the functional basis of reactive aggression, while the right posterior cingulate may be the functional basis of the behavioral stimulation effect of idiosyncratic anger. The results showed that the functional connection intensity of the right amygdala to the right amygdala and the bilateral medial OFC, the left temporal pole and the bilateral medial OFC was significantly different. The functional connection intensity of the right amygdala and the right ACC was significant. Further analysis showed the functional connection intensity and reactive attack of the left temporal and bilateral medial OFC. In other words, the functional connection between the left temporal pole and the bilateral medial OFC may also be the basis of the brain function that the trait anger affects reactive aggression. To sum up, this study, from the perspective of the general attack model (GAM), explores the neural mechanism of idiosyncratic anger affecting attack behavior. The dynamic cognitive processing brain areas also involve efforts to control the brain area, provide brain scientific evidence for the general attack model (GAM) as well as the theory of effort control, and have a positive impact on understanding the relationship between trait anger and aggressive behavior.
【学位授予单位】：西南大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：B845.1

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