depression acupuncture treatment Hamilton Rating＇Scale for D

  本文关键词：针刺联合西药治疗轻中度抑郁症患者88例临床观察，由笔耕文化传播整理发布。

针刺联合西药治疗轻中度抑郁症患者88例临床观察

A Clinical Observation on Acupuncture Combined With Western Medicine for 88 Depression

[1] [2] [3] [4] [5] [6] [7]

MA Xuehong, YANG Xiuyan, XU Ke, PAN Li, YANG Xinjing, WANG Sihan, TU Ya （ 1. Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078 ; 2. Beijing Universi

[1]北京中医药大学东方医院,北京市丰台区方庄芳星园1区6号,100078; [2]北京中医药大学;,北京市丰台区方庄芳星园1区6号,100078; [3]北京大学第六医院;,北京市丰台区方庄芳星园1区6号,100078; [4]宁夏医科大学附属银川市中医医院,北京市丰台区方庄芳星园1区6号,100078;

文章摘要：目的通过采用基于患者报告临床结局的方式观察针刺联合西药抗抑郁的疗效。方法将88例轻、中度抑郁症患者随机分为电针组28例，手针组25例，药物组35例。药物组患者给予盐酸帕罗西汀片，治疗第1、2天每日10mg，每日1次，从第3天开始剂量增加到每日20mg，每日1次，共服用6用。手针组在药物组基础上配合针刺治疗，主穴：百会、印堂，基本配穴：风府、风池（双侧）、大椎、内关（双侧）、三阴交（双侧）；电针组在药物组基础上配合电针治疗，选穴同手针组，以百会和印堂、双侧风池连接于电针仪正负极，刺激频率选2／15Hz疏密交替波。手针组和电针组均隔天治疗1次，每次针刺30min，1周治疗3次，疗程6周。观察各组治疗前后汉密尔顿抑郁量表17项（HAMD-17）、基于患者报告的症状量表（MYMOP）评分变化情况，治疗后评价临床疗效。结果电针组临床疗效总有效率为89．28％、手针组为92．00％、药物组为85．71％，电针组和手针组优于药物组（P〈0．05）。各组患者治疗后MYMOP各项评分与本组治疗前比较差异均有统计学意义（P〈0．05），，并且电针组和手针组各项评分明显低于药物组（P〈0．05），而电针组和手针组各项评分比较差异无统计学意义（P〉0．05）。结论针刺联合西药可以显著降低轻、中度抑郁症患者HAMD．17及MYMOP评分，改善主要症状、总体健康状况和活动情况，优于单纯西药治疗。

Abstr：Objective To observe the therapeutic effect of acupuncture combined with western medicine for depression based on patient-reported outcomes （PROs）. Methods Totally 88 cases of mild to moderate depression were randomized into the electro-acupuncture （EA） group （28 cases）, manual acupuncture group （25 cases）, and western medicine group （35 cases）. The western medicine group was given Paroxetine Hydrochloride Tablets, 10 mg/ d during the first two days and 20 mg/d from the 3rd day of treatment for a total of six weeks. The manual acupuncture group and EA group were added with acupuncture or EA on the main acupoints of Baihui （ GV20 ） and Yintang （ EX- HN3） and basic acupoints of Fengfu （GV16）, Fengchi （GB20, bilateral）, Dazhui （GV14）, Neiguan （PC6, bilateral） and Sanyinjiao （ SP6, bilateral） on the basis of western medicine group. The manual acupuncture group and EA group were given acupuncture 30 min each time and once every other day for six weeks. The therapeutic effect was evaluated according to the Hamilton Rating Scale for Depression-17 items （HAMD-17） and the Measure Yourself Medical Outcome Profile （MYMOP）. Results The total effective rate of the EA group, manual acupuncture group and western medicine group were 89.28%, 92.00% and 85.71% respectively. The total effective rates of the EA group and manual acupuncture group were superior to that of the western medicine group. There were significant differences between before and after treatment in the scores of MYMOP in all groups （P 〈 O. 05 ）. The scores of MY- MOP in the EA group and manual acupuncture group were significantly lower than those in the western medicine group after treatment （ P 〈 0.05）. There was no significant difference bet

文章关键词：

Keyword：:depression acupuncture treatment Hamilton Rating＇Scale for Depression-17 items Measure Yourself Medical Outcome Profile

课题项目：基金项目：北京市科技计划资助项目（Z121100005512024）

作者信息：会员可见

  本文关键词：针刺联合西药治疗轻中度抑郁症患者88例临床观察，由笔耕文化传播整理发布。